![]() Shared and diverse underpinnings of psychiatric disorders cannot be systematically understood based on symptom-based categories of mental disorders, which map poorly onto pathophysiological mechanisms. It is widely acknowledged that comorbidity between psychiatric disorders is the rule rather than the exception. We will identify both shared and disorder-specific markers at different observational levels that can be used as targets for future diagnostic and treatment approaches. In October 2021, we are at 95% of our target.Ĭonclusions: The MIND-SET study enables us to investigate the mechanistic underpinnings of nonpsychotic psychiatric disorders transdiagnostically. Results: We aim to include a total of 650 patients and 150 neurotypical control participants in the time period between 20. The data collection procedure includes online questionnaires and three subsequent sessions with (1) standardized clinical examination, physical examination, and blood sampling (2) psychological constructs, neuropsychological tests, and biological marker sampling and (3) neuroimaging measures. Data collection started in June 2016 with the aim to include a total of 650 patients and 150 neurotypical controls by 2021. Individuals with no current or past psychiatric diagnosis are included as neurotypical controls. Included are adult (aged ≥18 years), nonpsychotic, psychiatric patients with a clinical diagnosis of a stress-related disorder (mood disorder, anxiety disorder, or substance use disorder) or a neurodevelopmental disorder (autism spectrum disorder or attention-deficit/hyperactivity disorder). Data from different observational levels as defined in the Research Domain Criteria (genetics, physiology, neuropsychology, system-level neuroimaging, behavior, self-report, and experimental neurocognitive paradigms) are collected over four time points. Methods: This is an observational cross-sectional study. ![]() Objective: The main aim of the MIND-SET project is to determine the shared and specific mechanisms of neurodevelopmental and stress-related psychiatric disorders at different observational levels. ![]() We test this approach to psychiatric problems in patients with frequently occurring psychiatric disorders and their comorbidities (excluding psychosis). In the Measuring Integrated Novel Dimensions in Neurodevelopmental and Stress-Related Mental Disorders (MIND-SET) study, we make use of current concepts of comorbidity that transcend the current diagnostic categories. Peer-Review Report by Emma Palmer (Reviewer AS): Īuthors' Response to Peer-Review Reports: īackground: It is widely acknowledged that comorbidity between psychiatric disorders is common. Peer-Review Report by Max Birk (Reviewer B): Online Journal of Public Health Informatics.Asian/Pacific Island Nursing Journal 17 articles.JMIR Bioinformatics and Biotechnology 38 articles.JMIR Biomedical Engineering 76 articles.Journal of Participatory Medicine 84 articles.JMIR Perioperative Medicine 102 articles.JMIR Rehabilitation and Assistive Technologies 236 articles.JMIR Pediatrics and Parenting 328 articles.Interactive Journal of Medical Research 347 articles.JMIR Public Health and Surveillance 1294 articles.Journal of Medical Internet Research 8141 articles.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |